{"id":3496,"date":"2021-01-12T09:42:32","date_gmt":"2021-01-12T14:42:32","guid":{"rendered":"https:\/\/ridefordad.ca\/funded-research\/generating-a-population-based-recurrence-risk-mapbased-on-psma-pet-imaging-to-guide-radiotherapy\/"},"modified":"2026-04-04T20:10:22","modified_gmt":"2026-04-05T00:10:22","slug":"generating-a-population-based-recurrence-risk-mapbased-on-psma-pet-imaging-to-guide-radiotherapy","status":"publish","type":"funded-research","link":"https:\/\/ridefordad.ca\/fr\/funded-research\/generating-a-population-based-recurrence-risk-mapbased-on-psma-pet-imaging-to-guide-radiotherapy\/","title":{"rendered":"G\u00e9n\u00e9ration d’une carte de risque de r\u00e9currence bas\u00e9e sur l’imagerie PSMA-PET pour guider la radioth\u00e9rapie."},"content":{"rendered":"

Une augmentation du taux de PSA d\u00e9tect\u00e9e peu apr\u00e8s une prostatectomie indique une r\u00e9cidive du cancer et touche 15 \u00e0 20 % des patients trait\u00e9s [Stephenson]. Les cellules canc\u00e9reuses r\u00e9currentes doivent \u00eatre compl\u00e8tement englob\u00e9es dans le volume clinique cibl\u00e9 (CTV) lors de la planification de la radioth\u00e9rapie afin d’am\u00e9liorer les r\u00e9sultats pour les patients. L’\u00e9mergence de l’imagerie PSMA-PET, qui a une sensibilit\u00e9 accrue dans la localisation des sites de r\u00e9currence de la maladie par rapport aux m\u00e9thodes conventionnelles, n’a pas encore la r\u00e9solution d’imagerie requise pour identifier certaines maladies de taille microscopique. La pr\u00e9sence de tels sites augmente le risque de r\u00e9cidive locale dans la r\u00e9gion pelvienne. Le pipeline de planification du traitement pourrait donc b\u00e9n\u00e9ficier d’une \u00e9valuation pr\u00e9alable de la r\u00e9currence dans la r\u00e9gion pelvienne \u00e0 partir de la population de patients malades. Les sch\u00e9mas de r\u00e9cidive locale dans cette population, accompagn\u00e9s de facteurs de risque, pourraient guider la d\u00e9limitation du CTV pour une planification fond\u00e9e sur des donn\u00e9es probantes. Cette combinaison d’informations pourrait \u00eatre pr\u00e9sent\u00e9e sous la forme d’une carte anatomique indiquant la probabilit\u00e9 de r\u00e9cidive dans la r\u00e9gion pelvienne. La r\u00e9currence de la maladie li\u00e9e aux structures anatomiques peut \u00eatre \u00e9valu\u00e9e \u00e0 partir de l’alignement des images PSMA-PET\/CT de chaque patient. La carte de probabilit\u00e9 peut \u00eatre d\u00e9riv\u00e9e de l’\u00e9valuation de l’occurrence li\u00e9e \u00e0 la localisation de la maladie dans la population de patients. Une telle carte de probabilit\u00e9 bas\u00e9e sur la population est prometteuse pour la planification du traitement et la couverture de la maladie pendant la planification de la radioth\u00e9rapie.<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"template":"","meta":{"_acf_changed":false,"_lmt_disableupdate":"","_lmt_disable":""},"class_list":["post-3496","funded-research","type-funded-research","status-publish","hentry"],"acf":[],"yoast_head":"\nG\u00e9n\u00e9ration d'une carte de risque de r\u00e9currence bas\u00e9e sur l'imagerie PSMA-PET pour guider la radioth\u00e9rapie. - Randon\u00e9e pour papa<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ridefordad.ca\/fr\/funded-research\/generating-a-population-based-recurrence-risk-mapbased-on-psma-pet-imaging-to-guide-radiotherapy\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"G\u00e9n\u00e9ration d'une carte de risque de r\u00e9currence bas\u00e9e sur l'imagerie PSMA-PET pour guider la radioth\u00e9rapie. - Randon\u00e9e pour papa\" \/>\n<meta property=\"og:description\" content=\"Une augmentation du taux de PSA d\u00e9tect\u00e9e peu apr\u00e8s une prostatectomie indique une r\u00e9cidive du cancer et touche 15 \u00e0 20 % des patients trait\u00e9s [Stephenson]. 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